01:447:390 Lecture Notes - Lecture 1: Thymine, Nucleoside, Oswald Avery
27 Feb 2018
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Ch 10 chromatin and chromosomes ch 13 pgs 358-360 (note 2 powerpoint files) ch 11 pgs. Transfer rna--carry amino acids in for polypeptide synthesis. Small nuclear rnas help process pre-mrnas into mrnas. Small nucleolar rnas help process and assemble ribosomal rnas. Some interfere with protein production, ex. micrornas (mirna), small interfering rnas (sirnas), interfering rnas. Piwi-interacting rnas suppress transcription of transposons in testes, interact with the piwi protein (p-element induced wimpy testis in drosophila) Crispr rnas help bacteria and archaea destroy invading viruses and plasmids. Some act as molecular decoys, and bind up proteins that would otherwise destabilize chromosomes. Others cause changes in the structure of chromosomes, inhibiting gene expression. Only 1-2% of the human genome encodes proteins; 80% of the human genome is transcribed. Contain the information that determines all the traits & functions of the organism. Be stable in general, but also have the ability to change in some ways without causing harm to the organism.
