01:447:380 Lecture Notes - Lecture 10: Allele, Chromosome, Asthma

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Rf between the c gene and the w gene = 13% Rf between the w gene and the t gene = 27% Interference = 9. 0: imagine you performed a linkage analysis in this family, looking to identify the gene mutation that is causing the disease that affects some of its members. You are trying to identify the location of the gene that is responsible for the autosomal dominant disease that is segregating through the family depicted below. Imagine you have conducted an association study, looking at the allele distribution of three genes in controls versus people who have asthma. Allele 4 0. 25 0. 20 0. 25 0. 05 0. 05 0. 05. Honors questions: in the following figure, you have a family that has several members affected with an autosomal dominant disorder. You see genotype information for three snps that lie on chromosome 4 (from the top down, call them snp 1, snp 2, snp 3).

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