01:694:215 Lecture Notes - Lecture 2: Interactive Media, Plasmid, Mutagen
Document Summary
Yeast, fruit fly, nematodes (soil worms), plants and mice- Cheap to house (on plates), do things in large mass, Transformable - can put dna back into cells. Humans have 1000 fold larger than e coli. Humans have 4 fold more genes than yeast. Human genes are spread out among junk dna, introns. Daughter cell pinches off of mother cell. Once pheremones are sensed, they come in contact with each other and the nuclei fuse (2 copies of genes diploid) If there is sugar, it will thrive. If not (dries up), it will replicate (4n) and go through meiosis (1n) haploid. Want to remain diploid- if one copy of the dna has a mutation, the other copy can be used as a template to fix the mutation. Genetic analysis- the characterization of mutants to investigate a biological process. Mendel- looked at phenotypes of pea pods. Yeast can make its own amino acids.