11:709:255 Lecture Notes - Lecture 13: Thiamine Pyrophosphate, Malnutrition, Heart Failure
25 Mar 2020
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Document Summary
Water-soluble vitamins part 1: the market for vitamin and mineral supplements is a multibillion dollar industry, water is an expensive way to get nutrients. Thiamin, b1: rda, men: 1. 2 mg/day, women: 1. 1 mg/day, chief functions in the body, part of coenzyme tpp (thiamin pyrophosphate) used in the metabolism of cho, branched-chain amino acids and pentoses, synthesis of neurotransmitters. Thiamin: deficiency disease, beriberi, wet, with edema, dry, with muscle wasting, deficiency symptoms, enlarged heart, cardiac failure, muscular weakness, apathy, poor short term memory, confusion, irritability, anorexia, weight loss. Thiamin-deficiency disease: wernicke-korsakoff syndrome, mainly in alcoholics, alcohol diminishes thiamin absorption, alcohol increases thiamine excretion, poor quality diet, consequences of deficiency, involuntary eye movement, double vision, ataxia: staggering, poor muscle coordination, mental confusion (drunken stupor) Deficiency of riboflavin: ariboflavinosis, glossitis, cheilosis, seborrheic dermatitis, stomatitis, eye disorder, throat disorder, nervous system disorder, occurs within 2 months, usually in combo with other deficiencies.
