01:830:310 Lecture Notes - Lecture 8: Diffuse Axonal Injury, Brain Damage, Blood Vessel

• School: Rutgers University
• Department: Psychology
• Course: 01:830:310
• Professor: Professor Mayhew

Document Summary

Edema - fluid buildup (can cause drowsiness or loss of consciousness) Cell infiltration: cells of the immune system. Vascular changes (early after injury, depends on severity of injury) Vasodilation - leads to increased blood flow causing redness and warmth. Increased permeability - leads to exudation of protein rich fluid into the extravascular space causing swelling. Concentration of red cells - caused by loss of fluid from vessels; results in decreased velocity and stasis of blood flow. Leukocyte rolling, adhesion and migration leads to accumulation of inflammatory cells. 80% of hospital admissions for head injury are mild tbi (mtbi) 15% of all evaluated sport-related injuries are concussions. Less than 50% of concussions are reported, so that percentage will likely rise. Coup - brain damage at site of blow. Contrecoup - brain damage opposite to site of blow. Coup-contrecoup - brain damage on both sites. Hemorrhage - an escape of blood from a ruptured blood vessel.