01:830:313 Lecture Notes - Lecture 41: Nmda Receptor Antagonist, Excitatory Postsynaptic Potential, Medial Geniculate Nucleus

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Plasticity - the quality of being shaped or molded. A stimulus that initially produces no particular response is paired several times with an unconditioned stimulus (us) that produces a defensive or appetitive response, the unconditioned response (ur). After conditioning, the conditioned stimulus (cs) elicits the conditioned response (cr). Nondeclarative memory - riding a bike, driving a car, muscle memory. Long-term potentiation: a long-term increase in the response of neurons to a particular synaptic input caused by patterned activity of that input. Currently, the best cellular model of learning/synaptic plasticity. Occurs in certain cns synapses, including mgm/pin synaptic connection to basolateral. The amygdala is important in classically conditioned emotional responses. Synaptic changes responsible for learning could take place in this location. Lateral nucleus of the amygdala contains neurons whose axons project to the central nucleus, terminal buttons from neurons that transmit auditory and somatosensory info to the lateral nucleus form synapses with dendritic spines on these neurons.

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