ENS 332 Lecture Notes - Lecture 7: Aortic Insufficiency, Aortic Aneurysm, Aortic Valve
18 Oct 2016
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Document Summary
Discovered a connective tissue disorder, affects fibrillin. Tend to be tall, have long appendages, and often have scoliosis. Autosomal dominant, just need one copy of the gene. Wrist sign fingers overlap around the wrist: one of the 30 physical signs used in diagnosis. Risk for the aorta bursting (aortic aneurysm) Valves tend to be affected mitral & aortic regurgitation: valves do not close properly. Pressure overload concentric remodeling invading the lumen: wall thickens impaired conduction loss of inotropy loss of strength of contraction. Leads to increase in end diastolic volume affects valves pulse pressure becomes wider. Pressure in the ventricles during diastolic increases: systolic pressures are higher due to hypertension, too much pressure and volume in the left ventricle during diastole puts more stress on the atria. Diagnosis for aortic regurgitation: listen at the angle of louie (second intercostal space) and aortic arch, faint crescendo sound after s2, no isovolumetric contraction or relaxation.
