ENS 332 Lecture 20: Musculoskeletal 2
Document Summary
Prevalence: >200 million worldwide, ~9% of adult us population, at least 30% of postmenopausal women in us and europe, ~10% of men over 80. Incidence: data unclear, more powerful incidence data on fractures. Mortality: risk of dying from hip fracture ~ equal to breast cancer mortality (10% at 5 year follow up) ~11 per 1000 person years in women. ~6 per 1000 person years in men. <10% of vertebral fractures end in hospitalization, even though many more are painful and result in disability. Fractures typically occur due to the compression in the vertebra: hip. Associated with more serious disability and mortality. Combined lifetime fracture risk is similar to cardiovascular disease risk. The mechanisms why cardiovascular risk is so much higher are not fully. Women with hip fracture have a 10-20% higher mortality risk. Risk is stratified by the age category. Provides: framework for movement, vital organ protection, calcium storage, hematopoiesis endocrine function of the skeleton.