ENS 333 Lecture Notes - Lecture 11: Nitric Oxide Synthase, Potassium Channel, Peripheral Artery Disease
Document Summary
Prognosis: no clear story to tell as the disease is so dependent on management. Mortality: 7th leading cause of death in us, ~230k deaths annually are due to diabetes or have diabetes as a major contributing factor, type 2 diabetes mellitus greatly increases risk when a comorbidity with other conditions. Patients surviving after having a myocardial infarction (mi) No type 2 diabetes and under 200 mg/dl standard survival over 200 days. Type 2 diabetes and over 200 mg/dl survival is much worse. No type 2 diabetes (diagnosis) and over 200 mg/dl worse case of survival: patients may not be getting access to the healthcare they need. Hba1c = glycated hemoglobin: form of hemoglobin after exposure to high blood glucose, indicative of glucose control over months. B) excess caloric intake leads to metabolic overload, increased tg input and the adipocyte enlargement.