BIO 202 Lecture Notes - Lecture 23: Cytokinesis, Interphase, G1 Phase
21 Apr 2016
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Even some bacteria, which divide continuously when conditions are good, can stop dividing if conditions are bad. Experiment 1: fuse a cell in m phase (where you can see mitotic spindle and breakdown of nuclear envelope) with a cell in g1 phase (interphase: just see chromatin filling the nucleus) Scientists artificially fused the cells because normally they would never fuse so now one huge cell. This one huge cell acted as if trying to go into mitosis (chromosomes condense, nuclear envelope fragmented, mitotic spindle forming etc. ) M cell was normal with replicated chromosome and two sister chromatids held together waiting to be pulled apart. G1 cell doesn"t have any replicated chromosomes so only the single copy of the chromosome condenses abnormal (it has no business going into m phase) Experiment 2: fuse a cell in s phase with a cell in g1 phase (other techniques used to tell them apart because can"t just look and tell)
