BIO 203 Lecture Notes - Lecture 23: Pathogen-Associated Molecular Pattern, Natural Killer Cell, Pattern Recognition Receptor

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Performed in two cases: non-functional bone marrow cells, cancers of bone marrow cells. Steps in transplants: patient matched with donor, patient"s bone marrow is killed with chemotherapy or radiation; all dividing cells die, donor bone marrow is removed and implanted into patient; donor bone marrow produces healthy blood cells. Immunology: the study of the physiological defenses by which the body recognizes itself from non-self: pathogen: any microbe that could cause disease, abnormal self cells: cancer, virally infected cells, old and dead cells. Most can survive and reproduce out side a host. Most can be killed or inhibited by antibiotics. Recognizes broad groups of foreign proteins not found in healthy cells. Not cells, nucleic acid core with protein coat. Cannot be killed with antibiotics, some can be inhibited with antiviral drugs. No memory; response to microbe is always the same speed and strength. Has memory; response to an antigen is faster and stronger the second time.

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