BIO 203 Lecture Notes - Lecture 1: Covalent Bond, Lipophilicity, Membrane Potential
Document Summary
1. permeability of lipid bilayer membrane becomes less leaky. Many calcium salts are insoluble e. g. calcium phosphate. Causes aggregation of nucleic acids and cellular processes proteins. Requires very low ca2+ concentration inside of cell. High internal k+ ion concentration: water molecules, 75% of total body weight and 99% total number of molecules, pure water, a poor conductor of electricity. Lecture 1 membrane potentials pumpstransporters - august 28, 2017 polar molecule polar covalent bonds electronegativity dipole. Cell membrane: barrier to diffusion of charged and polar molecules, lipid bilayers, phospholipids. Phospholipids: two distinct regions, polar - hydrophilic, interact with water molecules, nonpolar - hydrophobic, interacts with other hydrophobic molecules. Lecture 1 membrane potentials pumpstransporters - august 28, 2017 amphipathic hydrophobic core like thin layer of oil. Integral membrane proteins fluid mosaic model integral membrane proteins amphipathic membrane 60 (6 nm) thick hydrophobic core 30 (3 nm) thick.