BIO 203 Lecture Notes - Lecture 19: Innate Immune System, Cytotoxic T Cell, Adaptive Immune System

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Bacteria- cells surrounded by cell wall (prokaryotic), can reproduce outside of humans, can be killed/inhibited by antibiotics. Viruses- not cells (nucleic acid with protein coat) parasitic needing host cell to reproduce their dna proteins (cell hijack), can"t be killed with antibiotics (inhibited with antiviral drugs) Innate immune system- immune cells recognize varied groups of foreign proteins (pamps) not found on healthy host cells (esp. proteins/carbs found in bacterial cell walls), responds quickly with no memory (always same speed/strength). Adaptive (acquired) immune system- recognition of specific molecules found on microbes (antigen), reacts slowly (week+) but has memory (faster/stronger 2nd time), specific to vertebrates. Primary immune tissues- immune cells develop and mature. Thymus (t cells are trained ), bone marrow (immune cells develop/mature inside) Secondary immune tissues- immune cells intercept and interact with pathogens/abnormal host cells. Located in places where they can intercept pathogens from circulation. Diffuse lymphoid tissues- gut associated lt (galt) is the largest immune organ in body, tonsils.