BIO 325 Lecture Notes - Lecture 3: Fate Mapping, Paracrine Signalling, Juxtacrine Signalling
14 Sep 2018
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Chapter 2- specifying identity: mechanisms of developing patterning. Cell specification how cells become specified to a specific fate and explore how cells of different organisms use different mechanisms for determining cell fate. The generation of specialized cells types is called differentiation, a process during which a cell ceases to divide and develops specialized structural elements and distinct functional properties. During the course of commitment, the cell might not look different from its nearest or most distant neighbors in the embryo and show no visible signs of differentiation. Specification- when cell or tissue is capable of differentiating autonomously when placed in an environment that is neutral with respect to the developmental pathway. The blastomeres of the early embryo are apportioned a set of critical determination factors within the egg cytoplasm. Different regions of the egg contain different morphogenetic determinants that will influence the (cid:457)ell"s de(cid:922)elop(cid:510)e(cid:511)t.
