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CHE 113: Blood Typing POGIL

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CHE 113

Blood Typing How is a human sample analyzed to determine the blood type? ▯ Why? Blood is a complex mixture of cells, enzymes, proteins, and inorganic substances. Under- standing the different components of blood allows a scientist to use the components in sim- plex tests are performed in a crime laboratory.done one site at the crime scene, or more com- ▯ Learning Outcome ▪ Students will be able to distinguish between antigens and antibodies, and the uses of these two components in blood typing. ▪ Students will be able to apply genetic inheritance of blood typing using Punnet squares. ▯ New Concepts Blood is primarily made up of a fluid portion, called plasma, and three types of cells – erythrocytes, leukocytes, and platelets. ▯ Proteins found in blood are made from amino acids linked together through a ▯eptide bond. Serology, the study of the proteins found in blood, used in forensics will focus on the antigen / antibody protein connection to determine blood typing. ▯ ▪ Protein synthesis, DNA, chromosomes, genes, human reproduction ▯ Reading Assthnment Saferstein, 8 edition, pg. 328-346 ▯ ▯ ▯ ▯ ▯ ▯ ▯ Model 1 : The Mixture Known as Blood ▯ ▯ ▯ ▯ ▯ ▯ Other common Percentage Facts worth names used found knowing in whole blood Plasma - 55% - a clear yellowish fluid that sits on top can be milky in color after a fatty meal, due to the fat molecules being suspended Erythrocytes - Red blood - 45% - percentage of blood made up cells called the hematocrit commonly - shaped like a shallow bowl, called a biconcave disc - has NO nucleus, extruded out upon maturity - can change shape, allowing it to squeeze through very small spaces - contains hemoglobin, the protein that carries oxygen - have antigens on their surface, a protein with a specific shape that determines the
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