NSD 225 Lecture 1: Fat Soluble Vitamins

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Found with fats in foods: storage, excretion, toxicity. Retinoids chemical forms of preformed vitamin a: retinol, retinal, retinoic acid. Carotenoids yellow orange pigments synthesized by plants and many microorganisms: some are vitamin a precursors converted to retinoids, example: beta-carotene, provitamin converted into vitamin a. Immature cells change in structure and function to become specialized by changing gene expression (turning genes on and off) Rda: men = 900 micrograms/day, women = 700 micro/day. Sources: vitamin a in animal products (eggs, dairy), provitamin a in fruits and veggies, beta-carotene in orange, yellow, and dark green veggies. Deficiency: xerophthalmia (night blindness progressing to permanent blindness), abnormal jaw bone growth in children, increased infection. Excess: nausea, vomiting, headache, dizziness, blurred vision, lack of muscle coordination, birth defects, liver damage, bone fractures; excess b-carotene can cause hypercarotenemia. Made in skin with exposure to uv light.

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