PSY 315 Lecture Notes - Lecture 12: Anticoagulant, Ergot, Psilocybin
Document Summary
Hallucinogen = sensory perception in absence of any real external stimulus. Hallucinogens: atropine - rapidly absorbed, excreted in 24 hours, scopolamine = l-hyoscine l-hyosciamine. Mechanism of action: serotonin hypothesis: occupies receptors temporarily - inhibits 5-ht release, turnover of se is down. Family: solanacea (consolation), e. g. potato: eating potato leaves hallucinations, genera: atropa, hypocymus, mandragora, datura. Hyocymus niger = henbane (s & h) Datura stramonnium = jimsonweed (3 effective ingredients: atropine, scopolamine, l- hysociamine) Physostigmine (eserin) enhances ach, ache inhibitor: used for myasthenia gravis, glaucoma: calabar or odeal bean of nigeria, related to sarin, mustard gas, chemical weapons, long term effects: restlessness, tremors, confusion, ataxia, convulsions, sweating, salivation, circulatory collapse. Atropine (atropa belladonna) deadly nightshade belladonna: anti-ach hallucinogens antagonizes ache inhibitors, given against muscarine poisoning, poisoning: cheerful confused state, loss of speech mania, delirium violent convulsions, 3 effective ingredients: atropine, scopolamine, l-hysociamine. Mandrake - mandragora officinarum (3 effective ingredients: atropine, scopolamine, l-hysociamine: commonly used as sedative-hypnotic.
