BIMS 201 Lecture Notes - Lecture 3: Tumor Suppressor Gene, Sister Chromatids, Restriction Point

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Cell Division
Mitosis: the process of cell division in which one cell becomes two
identical daughter cell
Purpose - renew
G row
C ell death
Apoptosis: process of cell death in which cells signal
their own demise in a programmed way
S tarts in the mitochondria, all of ETC is disrupted
Mitochondria bursts -> lysosomes release all -
ases -> cell starts to eat itself and break down
own protein -> collapses on itself
Develop
Heal (regeneration)
NOTE - nerves can regenerate, just VERY slow!!
Cell Cycle
S phase - DNA synthesis
Replication of chromosomes
When a chromosome replicates itself, it produces a copy of
itself
S ister chromatids: joined at the centromere, are
identical!
Homologous chromosomes: one from mom, one from dad ->
same alleles
"count lines for chromatids, dots for chromosomes"
Replication: process of duplicating a chromosome
Happens once
O ccurs prior to division
Ends of the chromosomes -> telomeres
S hort arm - p arm, long arm - q arm
G phase - gap for growth
G 1
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