BIOL 113 Lecture Notes - Lecture 29: Tyrosine Kinase, Signal Transduction, Paracrine Signalling
8 Jan 2018
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Friday, o(cid:272)to(cid:271)er (cid:1006)(cid:1011), (cid:1006)(cid:1004)(cid:1005)(cid:1011) (cid:1012):(cid:1006)5 am: cell directly sends only chemical signals - they use chemical language. We need the signal and then we need a receptor to be triggered, after the signal and receptor have combined/met it will lead to several (can be different) downstream effects. Need signal molecule, receptor molecule = cellular responses: cell signaling is central to modern medicine. Cancer: cell growing out of control - so it is not responding to cell signals properly. Diabetes: insulin to adjust sugar concentration in blood to keep homeostasis - but if cell isn"t responding to insulin then cell is out of control. Aids: pathogens mimic or interrupt normal cell communication to cause problems and that"s how it destroys immune system. Cholera: caused by bacteria can produce toxin which messes up cell signal and pathway. Cells communicate with each other: yeast, multicellular organisms. Cells send and receive information (signals: signaling molecules, receptors.
