NRSC 335 Lecture 20: motivation

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6-o hda destroys ascending dopamine neurons: medial forebrain bundle. Lh cell lesions = aversive taste reactions: neurons fire to sight of food. Hunger: hunger and hypothalamus, ventromedial hypothalamus (vmh, hyperphagia (eat a lot, altered metabolism, taste pleasure, vmh lesions. P araventricular nucleus: o vereat palatable food, r eject unpalatable food, hyperinsulinemia, more prone to store fat. S erotonin: activates p vn, decreases meal size. Leptin is fat satiety signal: tells you that you are full. E ating disorders: o vereating/obesity, g enetic control, o bese gene disrupts leptin, animals and humans gain weight, undereating, anorexia nervosa, r educe food intake, mostly women, begins in adolescence. Fear of becoming fat or losing control - distorted body image: bulimia nervosa, dieting and overeating alternate, disturbed serotonin activity. Female is the default sex of the brain. C astrated genetic male (no testes/testosterone: o variectomized (no ovaries/estrogen) genetic female, male sex develops if testosterone is in bloodstream, normal genetic male.

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