VIBS 204 Lecture Notes - Lecture 3: Tetrodotoxin, Aflatoxin B1, Lycopene

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Food toxicology and safety (vibs 204) unit 3. Mycotoxins- (myco-->fungi) toxic metabolites of fungi that frequently occur in food and feed and have been strongly implicated in diseases and death in man and animals; more than 300 mycotoxins identified. Mycotoxicoses- the diseases that result from mycotoxin exposure (e. g. aflatoxicosis is the disease caused by aflatoxin) Mycoses- diseases caused by infection with fungi (e. g. dermatomycoses- skin disease caused by fungi, or ringworm) Diverse class of secondary metabolites of fungi. More than 300 mycotoxins have been detected but relatively few are considered to be important to animal health. Prevalence and concentration are sporadic and vary annually, even in the same location. They may be produced pre- or post-harvest. Pre-harvest moisture (drought: optimal temperature range, mechanical damage to the plant o o. After the producing fungus aflatoxin named from aspergillus flavus; a-fla-toxin; a from aspergillus; fla from flavus and + toxin. Aflatoxin b1 (afb1) is the most potent naturally occurring liver carcinogen known.

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