BIOL 1001 Lecture Notes - Lecture 13: Sister Chromatids, Ploidy, Y Chromosome

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Stages of meiosis: meiosis i, prophase i, metaphase i, anaphase i, telophase i, no interphase ii. Random alignment of maternal and paternal chromosomes: during transition between prophase i and metaphase i, microtubules from spindle poles attach to kinetochores of chromosomes. Initial contacts between microtubules and chromosomes are random this is extremely important and allows mixing and maternal and paternal alleles of genes during meiosis i: maternal and paternal genes are passed on to offspring via meiosis. Crossing over during meiosis i (prophase i: each chromosome becomes zippered to its homologue, all four chromatids are closely aligned and form a chiasma, non-sister chromosomes exchange segments, occurs during prophase i of meiosis i. Human y chromosome and crossing over: fewer than two dozen genes identified, one is the master gene for male sex determination called the sry gene (sex-determining region of y)

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