BIOL 2112 Lecture Notes - Lecture 5: Ph Meter, Conjugate Acid, Acid Dissociation Constant

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Lecture 5 - supplement and study guide acids, bases, and buffers: a. In the following reaction, which is the acid and which is the conjugate base? (lecture 4, slide 2) Ha h+ + a: the tendency of an acid to form its conjugate base is shown in the following equation: Analogous to ph is the pka, defined by the following equation: pka = log 1/ka = -log ka. The pka is the measure of a tendency of a functional group to donate a proton. In a manner analogous to ph, that tendency decreases 10-fold as pka increases by 1 unit: does the dissociation constant, ka, become larger or smaller with the increasing strength of an acid? (slide 2) Ka becomes larger when the pka decresed: a. How is the pka related to the dissociation constant, ka? (slide 2) B. formic acid has a pka of 3. 74; acetic acid has a pka of 4. 76.

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