BIO 3372 Lecture 24: Chapter 24 - Microbial Diseases of Respiratory System
Document Summary
Upper respiratory system: nose, pharynx, middle ear, and eustachian tubes saliva and tears protect mucosal surfaces. Lower respiratory system: larynx, trachea, bronchial tubes, and alveoli. Ciliary escalator moves particles to the throat via ciliary action alveolar macrophages destroy microorganisms in the lungs. A wide variety of microorganisms colonize the upper respiratory tract. Normal microbiota suppresses pathogens by competing for nutrients and producing inhibitory substances. Lower respiratory system is nearly sterile due to the ciliary escalator in the bronchial tubes. Pharyngitis - sore throat, in ammation of mucus membranes in the throat. Laryngitis - larynx is the site of infection. Sinusitis - heavy mucus discharge from the sinuses if opening is blocked, then pressure and pain occur usually self-limiting. Epiglottis - ap like structure that prevents ingested material from entering the larynz most life threatening disease of the upper respiratory system; develops rapidly with death in a few hours. Streptokinase - lyse clots streptolysins - cytotoxic to cells.
