BIOL 201 Lecture Notes - Lecture 10: Centromere, Apoptosis, Aneuploidy

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Chromatin is a complex of dna (40%) and proteins (60%): domains of chromatin: Euchromatin: expressed: structure of chromosome: if we zoom in on a chromosome we will find the double helix dna coiled around 8 histones proteins. Histones are positively charged because of the presence of amino acids arginine and lysine. The complex of histone proteins and dna is known as nucleosome: cell cycle: the cell cycle is divided into five phases, g1: longest phase for most cells. Fills the gap between cytokinesis and dna synthesis: s: cell synthesizes a replica of the genome, g2: second growth phase. Prepares cells for the separation after the genome is newly replicated. During this phase, microtubules reorganize to form spindles: mitosis: division of the nucleus. the spindle apparatus assembles. Binds to the chromosomes and moves the sister chromatids apart. Mitosis is divided: walther fleming first discovered chromosomes, mitos means thread, most eukaryotes have between 10 and.

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