PSYC 465 Lecture Notes - Lecture 3: Resting Potential, Reference Electrode, Biological Membrane

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Oscilloscope: records the difference in mv between electrodes. Difference would be 0 if both electrodes are suspended in the same liquid environment outside the neuron (extracellular) When the recording electrode is inserted into the neuron (intracellular) and the reference electrode remains on the outside, the difference between the two electrodes becomes -70 mv the resting membrane potential of a neuron. During an action potential, mv rise dramatically to some positive mv and drop back down. Some things are allowed to pass through the membrane while others are not. If a substance is allowed, it will continue to flow into a cell until equilibrium is achieved on the outside and inside of the cell. If sodium chloride (nacl) is placed into the distilled water, it will begin to ionize (na+, cl-), or dissolve into the water. If the membrane allows, concentrations of na+ and cl- will become equal on the inside and outside of the membrane.

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