BIO 121 Lecture Notes - Lecture 23: Coronary Circulation, Nitric Oxide, Calcium Channel Blocker

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Starling"s forces 2 opps forces maintain w. r balance. Blood pressure forces w. r & small solutes out: occurs on arteriole side. Osmotic pressure pulls w. r back into capillaries (b/c of large proteins that can"t leave) Blood pressure higher than osmotic pressure (in arterioles) w. r leaves capillaries. At venule odd blood pressure falls below osmotic pressure fluid pulled back into capillaries. In resting person sitting upright blood pools in veins of lower body decrease blood flow rate. Coronary heart disease (chd) particularly in the coronary arteries. Narrowing of small blood vessels that supply blood & oxygen to heart. Treatment includes: aspirin, calcium channel blockers, nitrates, statins. Plaque forms smooth muscle cells migrate deeper attract lipids plaque fatty + muscle cells also prod fibrous connective tissue so artery hardens artery becomes narrow. 2 coronary arteries which are major blood supply to heart muscle.