ANA 113 Lecture Notes - Lecture 6: Loose Connective Tissue, Embryonic Stem Cell, Lipid Droplet

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C ells of c onnective t is s ue p roper. Produce fibers and ground substance of the extracellular matrix. Abundant, large, relatively flat cells, often with tapered ends. Fat cells with a single large lipid droplet; cellular components pushed to one side. Fixed macrophages large cells derived from monocytes in blood; reside in extracellular matrix after leaving the blood. Mesenchymal cells stellate or spindle-shaped embryonic stem cells. Small cells with a distinct nucleus derived from activated b-lymphocytes. Free macrophages mobile phagocytic cells formed from monocytes of the blood. Other leukocytes white blood cells that enter connective tissue. Divide in response to injury to produce new connective tissue cells. Repair damaged extracellular matrix; active in immune response. Release histamine and heparin to stimulate local inflammation. Form antibodies that bind to foreign substances, bacteria, viruses. Attack foreign materials (lymphocytes) or directly combat bacteria (neutrophils) C onnective t is s ue p roper.

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