BIO 205 Lecture Notes - Lecture 33: Symporter, Oxidative Phosphorylation, Phos
Lecture 33 Electron Transport and ATP Synthesis
Oxidation/Reduction
1. Oxidation = loss of electron density
2. Combining two reduction half-reactions
Electron transport
3. Anatomy of eukaryotic cell
a. Glycolysis occurs
b. Contain some DNA coding for some of the mitochondrial
metabolism proteins
c. They contain ribosomes for translating mRNA made from the
genes
d. They undergo division
e. They are same size as bacteria
4. Electron transport: 3 complexes process NADH
a. Complex 1: processes NADH
b. Complex 2: processes succinate and FADH
c. 1 NADH = 3 ATP made = 3H+
d. 1 FADH2 = 2 ATP made = 2H+
e. Complex 1: NADH-CoQ oxidoreductase
f. Complex 2: Succinate-CoQ oxidoreductase
g. Complex 3: CoQ-cytochrome c oxidoreductase
h. Complex 4: cytochrome c oxidase
Gradient driven ATP synthesis
5. Electron transport/ H+ gradient/ oxidative phos
a. Oxidative phosphorylation = e- transport + gradient driven
ATP synthesis
6. ATP synthase: quaternary structure
a. F0 (rotor) 1st
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