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Lecture 7

ANSC 101 Lecture Notes - Lecture 7: Chemotaxis, Antigen, Neutrophil


Department
Animal Science
Course Code
ANSC 101
Professor
Kasey Moyes
Lecture
7

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Immunity
System that allows for the identification of a foreign particle and the subsequent
destruction or metabolism of that particle
Ability to resist infections or toxins
Is NOT absolute, immunity exists in varying degrees
Immune system
Leukocyte: white blood cell; cell of the immune system
Form 1: Innate
o Non-specific
o Neutrophils and macrophages
o Macrophages
Recruit neutrophils (PMN)
Phagocytose (i.e. engulf and kill)
Antigen presentation
o PMN
Chemotaxis
Phagocytose
Form 2: Adaptive
o Specific
o Vaccine development
o Lymphocytes
T and B (antibody [Ig] production)
Immunity
Innate (non-specific) genetically determined, present at birth
o Neutrophils and macrophages
o Ex: skin, secretions that coat the respiratory tract, etc.
Adaptive (acquired, specific)
o Memory
T and B lymphocytes
o Occurs after encountering foreign substances (antigens)
o Made up of antibodies/antigens
Immunoglobulins; IgG, IgM, and IgA
Forms of Adaptive Immunity
Humoral (B cell lymphocytes, antibodies)
o Antibodies produced in response to antigens antigen specific response
Cell-mediated (T cell lymphocyte)
o Effective against viruses or bacteria that replicate within cells after crossing cell
membranes
o Circulating antibodies are too large to cross cell barriers
Adaptive Immune System 2 phases
Passive
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