BSCI 201 Lecture Notes - Muscle Relaxant, Sliding Filament Theory, Sarcomere
17 Mar 2014
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Document Summary
In a relaxed skeletal muscle, the overlap between thick/ thin filament is not complete. Incomplete overlap between the alternating thick/ thin filaments in the myofibril. *sarcomere description- part of a myofibril between 2 successive z discs. In center of sarcomere= thick filaments a bands. Skeletal muscle- skeletal muscle fibers run the entire length of the skeletal muscle (organ) Myofibrils run entire length of skeletal muscle fibers sarcomeres arranged end to end through the entire length of the myofibril. Skeletal muscle fiber: myofibrils consist of 2 types of filaments [actin and myosin, myoglobin- red pigment that bind/ release oxygen. [oxygen required for aerobic catabolism of glucose: mitochondria- sites for aerobic catabolism, sarcoplasmic reticulum- specialized smooth endoplasmic reticulum (sequester/ store/ release calcium into sarcoplasm) Calcium release is required for muscle contraction. Each sr has 2 expanded ends called terminal. Cisternae: sarcolemma has deep invagination called transverse.
