BSCI 202 Lecture Notes - Lecture 6: Cytotoxic T Cell, Bone Marrow, Immunocompetence

37 views3 pages

Document Summary

Occurs on second encounter with foreign matter. Any substance that can provoke immune response. Antigens: complex proteins/polysaccharides, part of a foreign invader/tumor cells, epitopes= recognition sites on pathogen/antigens for b or t cells. B and t cell specificity: antigen receptors recognize certain antigens only, b cells- membrane antibodies, t cells- t cell receptors. Immune cells should not attack our own proteins. Immune cells may view transplant as foreign (rejection) Immunocompetence occurs when immune cells become capable of responding to a specific antigens by binding to it. Lymphocytes: originate from hemocytoblasts in the red bone marrow, b lymphocytes become immunocompetent in the bone marrow, t lymphocytes become immunocompetent in the thymus. Macrophages: arise from monocyte, widely distributed in lymphoid organs, secrete cytokines. B+t cells do not attack normal cells of body. Self-tolerance- as cells develop in bone marrow and thymus, any that have antigen receptors against normal body cells are destroyed by apoptosis (programmed cell death)

Get access

Grade+20% off
$8 USD/m$10 USD/m
Billed $96 USD annually
Grade+
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
40 Verified Answers
Class+
$8 USD/m
Billed $96 USD annually
Class+
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
30 Verified Answers

Related Documents

Related Questions