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Lecture 1

BSCI 223 Lecture Notes - Lecture 1: Haemophilus Influenzae, Streptococcus, Middle Ear


Department
Biological Sciences Program
Course Code
BSCI 223
Professor
mciver
Lecture
1

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3.1a If Fredrica has an ear infection caused by
Streptococcus pneumoniae, why doesn’t she get
pneumonia? Could you isolate S. pneumoniae from your
nasal cavity? Explain.
The form of Streptococcus pneumonia that has invaded
Fredrica’s ear only causes ear infections and not pneumonia.
Since she is not contagious, then she will not get
pneumonia- which is contagious. [ndhealth.gov] If
Streptococcus pneumonia invaded the throat, then it would
be possible for her to get pneumonia.
According to Koch’s postulates, an infectious microbe can be
isolated from the diseased host and isolated onto pure
culture. [lecture]
3.1b
What are some possible components of the pus found in
the middle ear? How does this produce the redness of
the eardrum? How does this relate to fever?
It is possible that if Hemophilus influenzae is the disease
causing bacteria, endotoxins were released because it is
gram negative. The lipid A component of LPS of the gram –
cell wall are found in the pus. When the bacteria evades the
host cell, it can cause the immune system to overreact
causing an inflammatory response. Fevers are associated
because endotoxins produce the same effects (chills, aches,
fevers…etc) [lecture]
3.1c
Wanda believes that amoxicillin will always be able to
cure Fredrica of her ear infections. What are two
scenarios where this antimicrobial drug will not be
useful in treating her otitis media symptoms?
-Amoxicillin was first able to cure Wanda of her ear infection, but
after continuous use, the bacteria causing the infection will mature
after some amount of generations to possibly contain resistance to
this antimicrobial drug.
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