KNES 300 Lecture Notes - Lecture 10: Bill Bowerman, Prosthesis, Ecker
27 Feb 2017
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Could t-rex catch a jeep: speed about 40 mph (17. 9 m/s, usain bolt: 10. 2 m/s. Could t-rex even run: weighed about 6. 5 tons, largest extant land mammal (cid:523)elephant(cid:524) can"t run, wide range of estimates (0-25 m/s, estimations based on static analyses. Why not do dynamic analyses: no subjects available. Jurassic park method wont actually work: build a computer model. Solution: sensitivity analysis: assume a reasonable value (fossil, live animals, repeat study with different values. Tons of studies on this: 25 years of research, every sort of study design. Near unanimous conclusion: running not associated or predictive of knee oa, even over a lifetime. Evolutionary perspective: makes sense: bramble and lieberman (2004) Genetic predisposition: no direct evidence, seems unlikely (lots of runners) Maybe peak load isn"t the problem: cartilage response to loading, rabbit model (videman, 1982) Sedentary time: sitting, too much is bad. Reduce physical inactivity: stand more, standing desks (office, school) Cartilage likes cyclical loading: locomotion, synovial fluid.
