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Lecture 16

PHSC 401 Lecture Notes - Lecture 16: Giovanni Battista Grassi, Avian Malaria, Quinine


Department
Public Health Science
Course Code
PHSC 401
Professor
Boyle
Lecture
16

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PHSC401: Malaria 1 3/27/17
Malaria: humors
Galen (humoral explanation)
o Caused by imbalance
Reestablish balance: recommend bleeding/purging
o Explains origins of disease
Predisposition
o Diathesis: constitution
Occasional causes: emotional strain, over-worked, shock, illness, etc.
Miasmas:
Environment
o It was a form of bad air
o Somehow a susceptible person inhaled bad air
Got into the body or was absorbed through skin, and led to fever
Perhaps a chemical or later, a germ
o Sometimes called plaudisme, from the word swamp
Swamp fever
Intermittent fever:
Different timings of fever
o Tertian fever: every 48 hours
o Quartan fever: every 72 hours
o Quotidian fever: every 24 hours
1889: Camillo Golgi studied lifestyle of parasite and related timing of fevers to lifestyle of two
parasitic organisms
o Quotidian fever means there is more than one species of the parasite in bloodstream
Max van Pettenkofer:
Anti-contagionist
o Mainly concerned with cholera
Gives attention to local environment, has implications for malaria
Not a contagious disease
o Pathological material enters the body, it is not excreted
Cannot be transmitted from person to person
Before Tropical Medicine:
Diseases of the Tropics: middle of 18c to 1890s
Europeans affected by special diseases that arose as a result of conditions peculiar to warm
climates
o Resulting conditions of temp, humidity, and local ecology
Diseases were not different in nature from those in Europe, were not heightened in virulence
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