Class Notes (1,100,000)
US (470,000)
UM (4,000)
BIL (400)
BIL 250 (20)
Lecture 7

BIL 250 Lecture Notes - Lecture 7: Peptide Bond, Kozak Consensus Sequence, Initiation Factor


Department
Biology
Course Code
BIL 250
Professor
Kevin Mc Cracken
Lecture
7

This preview shows half of the first page. to view the full 3 pages of the document.
Translation
-Non-polar amino acid are the ones that are prevalent in the membrane
- Protein Kinase adds the phosphorylated protein
- Protein phosphatase does the opposite
Monomeric→ 1 polypeptide subunits
Dimeric→ 2 polypeptide subunits
Trimeric→ 3
TRANSLATION MECHANISMS:
Protein synthesis occurs on ribosomes
Protein is synthesized from the N terminus to the C terminus
mRNA translated from 5’ to 3’
Amino acid is attached to the stem on the tRNA.
The anticodon recognizes the amino acid, not the codon
4 steps of Translation
1. Charging of tRNA
2. Initiation
3. Elongation
4. Termination
1.
Aminoacyl-tRNA synthetase attaches to amino acids to a charged tRNA
Two phosphates lost, the last phosphate enters the cleft
2.
Initiation requirements
- mRNA
- Ribosome
find more resources at oneclass.com
find more resources at oneclass.com
You're Reading a Preview

Unlock to view full version