BIL 268 Lecture Notes - Lecture 22: Cell Migration, Pyramidal Cell, Neuroglia
Document Summary
A cell in the ventricular zone extends a process that reaches upward the pia. The nucleus of the cell migrates upward from the ventricular surface toward the pial surface; the cell"s dna is copied. The nucleus, containing two complete copies of genetic instructions, settles back to the ventricular surface. The cell retracts its arm from the pial surface. The newly daughter cells is cleaved vertically during division. After, the vertical cleavage, bot daughter cells remain in the ventricular zone to divide again and again. Later in development to expand the population of neuronal precursors, horizontal cleavage is the rule. In this case, the daughter cell lying farthest away from the ventricular surface migrates away to take up its position in the cortex. They will repeat the patterns until all the neurons and glia of the cortex have been generated. The adult ventricular zone retains some capacity to generate new neurons.