BIL 150 Lecture Notes - Lecture 30: Centromere, Telomere, Tandem Repeat
Document Summary
Genomes and their evolution: genomics is the study of whole sets of genes and their interaction, bioinformatics is the application of computational methods to the storage and analysis of biological data. Shotgun approach: the approach sequences random dna fragments directly, powerful computer programs are used to order fragments into a continuous sequence. Genbank the database of sequences: doubles its data every 18 months. Understanding genes and their products at the system level: proteomics is the study of all proteins encoded by a genome and their interactions. Systems biology: treatments of cancer and other disease can be individually tailored following analysis of gene expression patterns, dna sequencing may highlight diseases to which a person is predisposed. Genomes vary in size, number if genes and gene density: genes are sparsely distributed in the human genome, complex organisms have less introns.
