BIL 250 Lecture Notes - Lecture 13: Sister Chromatids, Separase, Nuclear Membrane

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Two periods during interphase when no dna synthesis occurs. During these periods, as well as s phase, intensive metabolic activity, cell growth, and cell differentiation are evident. End of g2 the volume of the cell has roughly doubles, dna has been replicated, and mitosis is initiated. Most variation is seen in the length of time spent in the g1 stage. Withdraw from the cycle and enter g0 stage. Cells that enter g0 stage remain viable and metabolically active but are not proliferative. Become committed to proceed through g1, initiating dna synthesis, and completing the cycle. Once g1, s, and g2 are completed mitosis is initiated. Migration of 2 pairs of centrioles to opposite ends of the cell. Each pair consists of one mature unit and a smaller, newly formed daughter. Nuclear envelop begins to break down and gradually disappears. Diffuse chromatin fibers have begun to condense, until distinct threadlike structures, the chromosomes, become visible.

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