BIL 360 Lecture Notes - Lecture 2: Tryptophan, Catecholamine, Chemical Classification

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Endocrine and neruroendocrine phsyiology (chemical messengers are hormones) Action potential travels through axon which causes release of neurotransmitters and travel short disntace to receptor mlc. Carried through bloodstream and can affect large populations of cells: any cells that have connection to bloodstream (which most do) they can be affected by hormones. Chemical substance produced and released by nonneural endocrine cells or by neurons; exerts regulatory influences on the cuntion of other distant cells reached via the blood; effective at low concentrations. Not hormones if they travel through synaptic cleft. Mechanism by how they are affecting target cells is what is putting them in one category or another. Both capable of producing hormones but have different origins. Neurosecretory are nervous in origin and nonneural is epithelial in origin. Target cells will express receptor molecules in cell membrane and intracellular receptors. Upregulating and downregulating sensitivity based on receptors produced. May also have multiple different receptor types.

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