BMB 401 Lecture Notes - Lecture 2: Deoxyribose, Ribosomal Rna, Ribose

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B dna is thermodynamically stable and the common form of biological dna. There is also a and z dna but if we look at them they look a little off in the pictures. Sugar puckers are found in dna and these 2 different puckers are what leads to the differences from the slide before that we can see. B dna is basically a trans and then a and z are cis essentially. Also b dna is right handed and so is a but z is left handed. If we examine the differences by the numbers we see b has the intermediate diameter of the three conformations at 20a. B also has 10 bp / helical turn leading to 36 degrees per base pair. By adopting the trans (endo) conformation they are able to pucker out of the plane of the ring and minimize steric clashes between substituents. C3 endo is in a dna and c2 endo is b dna.

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