MIC 321 Lecture Notes - Lecture 20: Attenuated Vaccine, Hepatitis B Vaccine, Rotavirus Vaccine

30 views6 pages

Document Summary

Get abs against both smallpox and cowpox. 1 = it evolves slowly and epitopes are highly conserved. 2 = vaccine causes infection in the skin to induce innate and adaptive response. 3 = infects only humans, not other animals = no reservoirs in other animals: immunization schedule in usa, 2 ways to make vaccines : Killed/inactivated virus (influenza, rabies) whereby the virus particles cannot replicate. Attenuated live virus (mimics real infection and mutant form of virus that grows badly in humans) (measles, mumps, polio) Live attenuated bacterial vaccines are not that common: other type of bacterial vaccines are against specific toxins secreted by bacteria like as tetanus or diphtheria toxins. Use inactivated toxins without toxic subunit but toxic enough to get response: 3rd type is polysaccharide vaccines. Capsule on bacteria to stop complement opsonization and alternative pathway. Abs bound to capsule can induce clearance so that"s why we make this vaccine.

Get access

Grade+20% off
$8 USD/m$10 USD/m
Billed $96 USD annually
Grade+
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
40 Verified Answers
Class+
$8 USD/m
Billed $96 USD annually
Class+
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
30 Verified Answers

Related Documents