MIC 323 Lecture 4: Test 2

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9: not all strains are pathogenic and not all of those pathogenic in humans can cause diseases in other animals. Issue in pigs for instance because it spreads quickly (etec infects pigs particularly piglets) Hgt: hgt = phages, hgt = plasmids (can be self transmissible like the sex-pili, e. coli hardly ever takes up naked dna by itself so only can be done in the lab. Important to classify stuff not by species (we know its e. coli but what type is it?) Important to know how to treat if we need to at all: h antigen = flagella and k antigen = capsule, coli with munson. 14: examine lps because they all have lps but lots of variations in o antigen (branched carb of lps) Ehec have bloody diarrhea are much worse (o157: epec and ehec are 99% identical! Ehec much worse because it acquired shiga toxin = causes renal failure.

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