MCB 181R Lecture 10: Biology Chapter 9
6 Oct 2016
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Endocrine signaling: examples of endocrine signaling molecules are adrenaline, estrogen and testosterone. These hormones must travel from the ovaries or testes through the bloodstream to target cells in various tissues. Paracrine/ autocrine signaling: paracrine and autocrine signaling are especially important to multicellular organisms during embryonic development, paracrine signaling molecules travel distances of up to 20 cell diameters or a few hundred micrometers. Growth factors are small soluble molecules: paracrine signaling. This signal is received by all the cells directly touching through a protein called. Notch: notch expressing cells= supporting glial cells, delta-expressing cell= develops into a neuron. Receptor proteins on the surface of any given cell can be placed into one of three groups, according to the way they are activated: g protein-coupled receptors, receptor kinases, ligand-gated ion channels. Gdp: enzymes in the cytosol specifically degrade camp which stops the phosphorylation and activation of target proteins by pka.
