PSIO 303A Lecture Notes - Lecture 36: Sciatic Nerve, Intermediate Filament, Fallopian Tube
17 Nov 2016
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Block 3 - lecture 6 - framework for success, the cytoskeleton. Understand what microfilaments, intermediate filaments, and microtubules, what they are made of, their approximate dimension, and what they do. Know microtubules are a structural component of centrosomes, cilia, and flagella. Understand what is meant by the term motor protein. Know that motor proteins dynein and kinesin move along microtubules to carry cargo to different parts of the cell. Understand the principle of fast axonal transport and know which direction is anterograde or retrograde. The longest axon is found in the sciatic nerve cell and is about 1m long. An average cell"s diameter is 10 um, the axon projection is so much more longer than a cell body (the axon of the sciatic nerve is about 1m). This length can be very challenging for nerve cells. It is an elaborate arrangement of protein fibers that serve the following functions: Protein strands that can give the cell structural rigidity.
