BIOL 1543 Lecture Notes - Lecture 15: Rhesus Macaque, Feline Immunodeficiency Virus, Lentivirus
25 Aug 2016
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Glowing cats lecture add-on: gfp (green fluorescent protein) Causes organisms that possess gfp glow green/blue: fiv feline immunodeficiency virus. Only known non-primate lentivirus that causes aids-like symptoms: rhesus macaques have an anti-aids gene. What they did: took gfp gene (nucleic acid = dna) and stuck it to resus macaques anti-aids gene, injected into cat embryos. What they found: the glowing cats were resistant to fiv. Why do they have to glow: gfp is a reporter. Tells the scientist that the gene is there. No use experimenting on cats without gene. To express a gene is to make the protein. Ribosome is the structure on which translation happens: trna has p site and a site for bonding. Review: the flow of genetic information in the cell: dna rna protein. The sequence of codons in dna spells out the structure of a polypeptide. Dna strand transcription rna translation polypeptide (amino acid)
