BIOL 2081C Lecture Notes - Lecture 17: Interphase, Noncoding Dna, Microtubule
Document Summary
Today, we discuss features of the typical eukaryotic chromosome, repetitive sequences, centromeres and telomeres. Likely, you"ve heard before that telomere shortening is associated with ageing. So, we will focus in-class on the association between telomere length with stress and cancer. Reading assignment: hartl text, sections 7. 7 7. 9. Optional video: refresher on meiosis and mitosis: https://www. youtube. com/watch?v=qclmr9-yy7o and https://www. youtube. com/watch?annotation_id=annotation_380762&feature=iv&src_vid=qcl mr9-yy7o&v=l0k-enzoeom. Download and bring to class: (either print or on your computer) telomeres and stress. pdf: you will also need to be able to go to this link, http://www. geron. com/imetelstat, during class. Learning objectives: distinguish between highly repetitive sequences, middle repetitive sequences, and unique sequences in dna in terms of approximate percentage of genome, possible function and origin, and number/frequency of copies, unique sequences: Prokaryotes and viruses are completely all single copy sequences. 40% of the total genome of sea urchins. 70% of the d. melanogaster genome: highly repetitive sequences: 4-45% of the genome depending on species.
