BIOL 2081C Lecture Notes - Lecture 30: The Sequence, Zygote, Eukaryote
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Reading assignment: hartl text sections 16. 1, 16. 2, and 16. 5. Helpful and optional videos: snail shell coiling, an example of maternal effect: https://www. youtube. com/watch?v=rko68ubihpu, mitochondrial dna, link on this page: http://learn. genetics. utah. edu/content/basics/molgen, something you have probably seen a headline about, explained by hank: https://www. youtube. com/watch?v=gt4j7tmou9y. Learning objectives: using pedigrees, distinguish between dominant, recessive, autosomal, x-linked (lecture 11), and cytoplasmic (lecture 30) modes of inheritance. Today, we focus on cytoplasmic and mitochondrial inheritance. The pattern may be dominant or recessive, and males and females are usually affected with equal frequency. The majority of hereditary disorders are the result of a defective gene on an autosome. Kinds of autosomal inheritance are autosomal-dominant inheritance and autosomal-recessive inheritance. Autosomal recessive: both genes of interest (i. e. , one from each parent) on a paired chromosome have the same defect; if both parents have the recessive gene of interest, the likelihood of expression in progeny is 1:4. The inheritance pattern may be recessive or dominant.
