BMB 420 Lecture Notes - Lecture 10: Genderqueer, Innate Immune System, Immunodeficiency

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Presentation of tb and the body"s ability to clear it differs. It is a non-binary bacteria in its not just have it or don"t. Innate immune system can get rid of the bacteria before we even know we have it. Taken up by lungs and macrophages, can replicate inside host cells. Tubercules are a group of cells containing the bacteria, dead cells, and immune cells. It can disseminate in organs and liver and camp out for long periods. Back and forth between the bacteria and the immune system are what occurs during the latent infection. Some people can clear tb with no problem, to some it can be deadly as the body cannot kill the bacteria. Can remain active in a biofilm environment in a latent infection. Like pseudomonas, can form biofilms in the lungs. Tuberculosis is a condition, not an organism. Mycobacterium commonly causes the disease, but many organisms can cause one to acquire tuberculosis.

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