INTL 340 Lecture Notes - Lecture 18: Cervical Cancer, Global Health, Common Rule
2 Jul 2018
School
Department
Course
Professor
Week 9 Class 2
Bioethics & Global Health Research
● what is “responsible conduct of research” when we are considering global health research?
○ submit research through IRB (international review board) for approval
Ethical Principles and Challenges
● principles: autonomy, beneficence, justice
○ how do these apply across cultures, in international research?
■ Breast and cervical cancer in brazil and Honduras
■ 1st giving diagnosis to family members before the patient
■ ethical principle is individual autonomy but across cultures sometimes
the individual is really part of the family so it would be more unethical
to give this info to the patient without the support of their family
already knowing… interesting cultural differences
■ translating these across cultures is problematic
Informed Consent
● adult participants must consent to participate in research study
● written or verbal consent? non-literate groups?
○ adjustments needed
● vulnerable populations (pregnant women, children, prisoners)? other vulnerabilities?
○ if you plan to do research with these 3 groups, need to go through more hurdles to
protect them and their rights
○ vulnerability could be lacking access to medical care…participating in research could
mean having access to coveted medical care (could be seen as coercion)
● coercion? withholding services?
○ we solicit participation through clinics and hospitals
■ people may feel like they don’t have the ability to make an informed choice
bc they could be caught off guard
■ if researcher talks to doctor and asks for doctor to refer people to his study,
then people may think that they are being advised to participate in the study
by the doctor for their own benefit which is not really the case (a lot of
authority and trust invested in doctors… especially in certain cultures and
communities of poverty—> you wouldn't question what the doctor is saying or
suggesting)
■ if you are at the doctor for a different reason, your attention could be diverted
and you could be vulnerable
○ other more ethical ways to recruit?
■ identify the patients in the hospital, ask if you can visit them somewhere
that’s not the hospital, then explain the study in a different place and then ask
for their participation
■ give them time to process after explanation, don’t rush it
○ if someone does not want to participate in a study, it is not grounds for withholding
health care from them
● understanding of research
○ understand methods
● medical authority
find more resources at oneclass.com
find more resources at oneclass.com
Document Summary
Submit research through irb (international review board) for approval. Breast and cervical cancer in brazil and honduras. 1st giving diagnosis to family members before the patient. Adult participants must consent to participate in research study. If you plan to do research with these 3 groups, need to go through more hurdles to protect them and their rights. Vulnerability could be lacking access to medical care participating in research could mean having access to coveted medical care (could be seen as coercion) We solicit participation through clinics and hospitals. People may feel like they don"t have the ability to make an informed choice bc they could be caught off guard. If you are at the doctor for a different reason, your attention could be diverted and you could be vulnerable. Identify the patients in the hospital, ask if you can visit them somewhere that"s not the hospital, then explain the study in a different place and then ask for their participation.
